conclusions results of the current study showed the high prevalence of m. tuberculosis among the patients with lung cancer; therefore, it seems that continuous surveillance is essential to monitor the m. tuberculosis in the patients with lung cancer. results the subjects included 252 (66.3%) males and 128 (33.7%) females. based on cultural and microscopic methods, m. tuberculosis infection was ...

although acrometastases are rare but clinically they are considered important. their etiology is quite different from the metastases to other sites; bronchogenic carcinoma is by far the most frequent case. the prognosis is always similar to metastatic bronchial cancer with an average survival of three months. treatment may involve distal digital amputation or antalgic radiotherapy. the main dif...

background: the her-2/neu gene is located on chromosome 17q21 and encodes a 185-kda transmembrane glycoprotein with tyrosine kinase activity reported to be released in soluble form in various malignancies. objective: to evaluate the clinical significance of soluble her-2/neu as a diagnostic marker in lung cancer. methods: serum levels of soluble her-2/neu were measured in 43 patients with lung ...

introduction: lung cancer is one of the leading causes of cancer related deaths in the world. the incidence of lung cancer is increasing in india and there is a need to understand the natural history of this disease. aim of the study: to study the clinico- pathological- radiological profile of patients diagnosed with lung cancer from january 2013 to may 2015 at a tertiary care teaching hospital...

aims: the backbone of treatment in advanced non-small cell lung cancer is platinum-based doublet chemotherapy. we intended to compare the effectiveness of two commonly used regimens in real world practice. methods: this single institute, parallel comparative post marketing study included 100 patients with chemo-naïve advanced (stage iiib, iv) non-small cell lung cancer and eastern cooperative o...

objective(s): chemoresistance remains the main causes of treatment failure and mortality in cancer patients. there is an urgent need to investigate novel approaches to improve current therapeutic modalities and increase cancer patients' survival. induction of drug efflux due to overexpression of                  p-glycoproteins is considered as an important leading cause of multidrug resis...

background: lung cancer is one of the fatal cancers in iran while 12% of the mortalities are related to this cancer in the country. this active hospital-based study was undertaken to determine the occurrence of lung cancer in fars province, southern iran. methods: data including face-to-face interview with patients and a survey of their medical and demographic records in relation to all invasiv...

cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the efficacy and safety of gemcitabine and cisplatin combination. twentythree pati...

background lung cancer is one of the most common causes of death worldwide. although smoking and environmental pollutants are the most important risk factors of lung cancer, the role of infectious causes should also be considered in the pathogenesis and progress of lung cancer. objectives this study examined the relationship between helicobacter pylori and lung cancer through serology, real-tim...

background: epidemiological studies have probed the correlation between telomere length and the risk of lung cancer, but their findings are inconsistent in this regard.  the present meta-analysis study has been carried out to demonstrate the association between relative telomere length in peripheral blood leukocytes and the risk of lung cancer using an established q-pcr technique. methods: a sy...